Try one of the following solutions in the order presented. Once the issue is resolved there is no need to appy the following step.
1 - Check the folder \\CORE\ldmain\sdstatus, if not possible to access it, or if its overloaded with files then open a command prompt and delete all files on that folder.
This is a Microsoft issue where Windows has difficulties handling/accessing folders with a large number of files.
2 - Reinstalling apmservice by executing:
"c:\Program Files\LANDesk\ManagementSuite\apmservice.exe" /register
3 - Open 'apmservice.ini' file located in \\CORESERVER\ldmain and make sure it looks like this:
The second line needs to be commented out by adding a ';' to the beginning.
Then LANDesk Policy Server needs to be restarted.