After the installation of LANDESK Antivirus, clients cannot connect through Direct Access.
Note: LANDESK Antivirus uses the Kaspersky Endpoint Security 10 engine.
More details about Direct Access from Microsoft: https://technet.microsoft.com/en-gb/network/dd420463.aspx)
To solve this problem please add 'svchost.exe' to Trusted Applications list and disable port 443 monitoring for it.
More about Exclusions for Applications: Chapter 2. File System Protection by Kaspersky