Is there a product that integrates directly with Microsoft Exchange similar to GoldMine's legacy GISME product?
GoldMine discontinued their own product GISME in July of 2012, customers may consider the 3rd party add-on (Riva) for which information can be obtained from the developers website below
Server-side synchronization for CRM and email systems
Riva is the leader in CRM and email integration. Since 2008, we have developed server-side integrations for a dozen of the world’s best CRM systems – including GoldMine 2015, GoldMine 2014, GoldMine 2013, GoldMine 9.x, and GoldMine 8.5 – and five enterprise email platforms (view supported systems).
Riva syncs GoldMine directly to Exchange, Office 365, Gmail, Google Apps, IBM Notes and Domino, IBM SmartCloud Notes, IBM Verse, and Novell GroupWise. There are no client-side Outlook, Gmail or IBM Notes plug-ins to install, configure, manage, or fix. These are just two of the many reasons why Riva is trusted by over 1,500 companies, including 50 Fortune 500 customers, 15 of the largest banks in the world, numerous Global 1000 accounts, and hundreds of small and medium-sized businesses.
What this means to your sales, marketing, and support teams is that Riva provides seamless access to GoldMine contacts, calendars, tasks, and email from all email applications and leading smartphones and tablets. Companies use Riva to improve GoldMine adoption, to increase sales productivity, to reduce manual data entry, and to reduce the flip-flopping between CRM and email applications.