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Our environment is somewhat the same: Malwarebytes/Landesk/McAfee.
I had to exclude the Malwarebytes executable from the McAfee scans.
Two things to consider:
1)You may consider excluding the entire folder structure (not just 1 or 2 files) for Malwarebytes. (the freezing part may be an issue with a buffer overflow)
2) Check for an update on the Malwarebytes site.
The "Exclusions" have already been added to the Antivirus environment per Malwarebytes Support Staff. I excluded not only folders, but files as well. They also just updated their software, but it acts the same way.