What is the OS of the system you are trying to change?
We are using windows XP Sp3
You have a couple of options, but the easiest way is to create a script or batch file using cacls. Here is the syntax
I like cacls since it is on every XP box and old and useful. There are other ways (secedit, iCACLS.exe, etc...), but keep it simple
I agree with Zman.
The great thing with a cacls script is it also works with Windows 7, should your organization eye a move.
Make sure you use the /T switch. Setting permission on the top level folder does not inherit to child items by default. This switch will ensure all child folders and files get the same permission.
You also have to use local security groups, if I'm not mistaking. You can't use domain security groups with cacls.