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You can add a button or hyperlink which will open a new mail with the subject pre configured to the existing mail subject and then set the main body of the email to say either Approved or Denied. You can change which words are used in the email configuration options of ISM.
I typically use a mailto: link with the return address,subject and body calculated as part of my sending mail something like mailto:firstname.lastname@example.org?subject=Approval%23%20$(ApprovlaNumber)&Body=Approved
Thank you very much for your thoughtful response.
I will test this and come back here if I encounter an issue