We can't really proceed without knowing the version of GoldMine you are running. Please publish that first.
I've run into this quite often with Office programs trying to use Goldmine. Your best bet is to uninstall GM Addins from control panel and remove from registry, I delete the following for all Outlook, word, and excel issues.
Once removed, reboot - then re-install the GM Addins. Next, run a reg file. The below will only work for Office 2007. Just open a note pad, paste, and save as a .reg then run it. It would be best to take a backup of your current registry before running just to be safe.
Thank you, Raven. I had resolved my issue by basically doing full and deep uninstall of office. Ugly solution but functional. Next time I will try this first.