Speed is likely impacted by the fact that as each message is being sent, it is writing information into GoldMine as it goes along. If you are often doing large mailings, IntelliSend (a module of IntelliClick email marketing), offers a way to handle large mailings efficiently. It also allows you to send on behalf of different users, including a batch process that can send mutliple batches for different senders simulaneously (i.e. different rep territories). More information is on the IntelliClick web site.
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What mail server are you using? The Exchange STMP connector uses a tarpit interval which will slow down sending emails from GoldMine (but can be changed).